The Playbook For The Modern Man

The Truth About Using Peptides & How They Impact Health

Get massive faster, but at what cost? We investigate…

There has been a great deal of discussion and controversy in the media around the use of peptides.

In light of this (and definitely not because I’m desperate to retain my youthful looks) I had a Sydney GP (who would prefer to remain nameless), who is asked several times a day by patients whether they can have peptides—and whether they’re even legal (he reckons a lot of people partially hope they are illegal).

The interesting thing about this is that most people who ask for them think of them as simply the latest in the ever-growing market of quick-fix magic potions.


When questioned by patients and friends for peptides and other weight-augmenting or weight loss medications, our GP always asks (and you should ask yourself too): What do you want to achieve? Is it legal (peptides are in fact completely legal, if prescribed by a doctor)? And: which are the right ones for you or me, as individuals?

Are Peptides Steroids?

The short answer is no. But it’s complicated. Let us explain: what are peptides?

In the world of health and fitness, peptides are used for increasing energy, burning fat, building muscle and improving athletic ability.

If you think of a hormone as a tree made up of many protein branches and even more peptide twigs, it’s easy to see how a hormone can have many side-effects if used wrongly.

Peptides on the other hand are much smaller and have been designed to stimulate specific receptors for growth hormone so you can tailor your results.

Essentially, they can be used for muscle gain or weight loss, recovery, reduced inflammation and are at the forefront of lots of new individual specific treatments for a range of disorders.

To begin with, we need to understand how our bodies function. At the base of our brain rests a small gland called the Pituitary Gland. Despite the fact that the Pituitary Gland is small, it is the control unit to other hormonal glands, for example, Adrenals and Thyroid, which are vital to a vast part of controlling your body and general wellbeing.

According to our medical source, in order to keep a sustainable balance in your body, the Pituitary Gland sends signals (hormones) into the circulatory system to the other organs and glands in your body to control or create their own hormones as needed.


“These hormones are keeping your body strong and healthy. Unfortunately, as we age they will start to decline.”

One of the hormones produced by the brain’s Pituitary Gland is Human Growth Hormone (GH or HGH). Human Growth Hormone keeps up body regulation, the digestive system and insulin levels.

But what signals the Pituitary Gland? Growth Hormone Releasing Hormone (GHRH), which originates from the Hypothalamus.

How Peptides Work

There are many kinds of peptides, which work on different areas of the body. Specifically, there are peptides that can increase our own body’s production of GHRH from the Hypothalamus to naturally release more Human Growth Hormone.

These Amino Acids stimulate our Pituitary Gland to make and excrete more of Human Growth Hormone into the bloodstream. The boosts in production will assist in potentially lessening the effects of ageing.

To understand the benefits of anti-aging, it is important to understand the benefits of increased Human Growth Hormone in the body. HGH acts on many tissues throughout the body. In children and adolescents, it stimulates the growth of bone and cartilage.

In people of all ages, it boosts protein production, promotes the utilisation of fat, interferes with the action of insulin, and raises blood sugar levels.

GH also raises levels of insulin-like growth factor-1 (IGF-1), which is important in the development of lean muscle and is a key factor in the negative feedback loop that causes decreased natural production and release of HGH from the pituitary when the hypothalamus is made aware of the level of HGH in the body.

This means that when there are low levels of HGH, the hypothalamus will release stimulators of HGH called Growth Hormone Releasing Hormones (GHRHs), and when the levels are high it will work to lower production.

This is one of the reasons that you should only take hormones prescribed by a doctor, so that you can help prevent the troughs when one stops hormones.

As peptides work on the GHRH receptors it goes around the negative feedback loop.


What’s Inside Peptides

Before looking at whether peptides are right for you, let’s look at what’s inside them.

Put simply, they are small proteins made up of fewer than 50 amino acids. Few amino acids have been more demonised of late than peptides for potentially giving unfair advantage in sports.

But as our GP says, “To brand all peptides evil would be like excommunicating poppies because of the plant’s link to drugs.”

“In small doses, and within medically approved and prescribed products, peptides can be a lacklustre complexion, body and life’s best friend.”

Peptides Injection

How do you take peptides? Well most peptides are injected into the body, but specialists are now developing other methods for introducing peptides into the body.

This includes creams which apply to the skin topically (outside of the skin) or transdermally (similar to patches). They can also be applied to the skin inside the mouth or consumed where it is then absorbed into the body.

Should You Use Peptides

When asking what you want to put in your body, you must always ask whether the benefits outweigh the side effects.

Like any substance that you know nothing about, they should not be bought online from unregistered suppliers (or borrowed from a friend).

Benefits Of Peptides

There is ample and robust evidence supporting the remedial effects of increased Human Growth Hormone.

As discussed by Harvard Men’s Health Watch, some of the benefits include; enjoying protection from fractures, increased muscle mass, decreased body fat, improved exercise capacity and a reduced risk of future heart disease.

A number of studies have also demonstrated improvements in psychological well-being, with specific improvements in energy improved sleep quality (fewer awakenings, increased duration of deep sleep). Moreover, healthcare consumption and sick days decrease in parallel with enhanced psychological well-being.


“Every man desires to live long,” wrote Jonathan Swift, “but no man would be old.” He was right, and the fountain of youth need not be an illusion.

There are a number of peptides that have been developed to assist the Pituitary Gland in releasing increased amounts of Growth Hormones.

Compared to steroids and testosterone, with their large potential for fast benefits and potential side effects, these are not magic beans that will turn you into a super-athlete overnight. Peptides are more of a medium burn for those of us that know that the body we want is one of lifestyle enhancement and that the hours at the gym are necessary.

Most people, when asked what they think a peptide is, simply don’t care. They are results-driven, and it doesn’t matter to them that their method might be madness. Peptides are a magic genie that is ready and waiting to enact your heart’s desire.

Like most things in life, success takes a little work and any help along the way is appreciated. The right plan and the right peptides can assist your body in doing the things it already does to achieve your desired results.

I myself have been using a range of peptides for many years and living a fast-paced, travel, work and event filled life I need to look natural, fit and healthy. More importantly, I need to look energetic and not tired—all of which peptides help me achieve.

Peptides Side Effects

They can have potentially serious side effects, so you should consult your doctor before even considering their use.

Used incorrectly, peptides have the potential to cause side effects of varying degrees depending on the user.

These can include:

  • Itchiness at the injection area
  • Increased water retention (a common sign of overdosage)
  • Increased hunger
  • Dry mouth
  • Tingling or numbness
  • High blood pressure
  • Extreme kidney pain
  • Joint pain
  • Darkening of moles and increase of freckles
  • Weight gain/loss
  • Decreased fertility

Peptides For Weight Loss

Many people are making a lot of money from selling what you want, so always remember to ask what it does, how long to take it, how to take it and what side effects it has so that you have realistic expectations of what it can do for (or to) you.


While peptides can help you to burn fat while working, eating, talking and even sleeping, they must be combined with other lifestyle factors over several months to see the best results.

RELATED: The Ketogenic Diet – The Truth About How It Impacts Your Health 

  • Jamminology

    Your full of shit

  • Michael McLean

    I have been on peptides for a year. I have taken a week and a half off and am getting fat and losing muscle fast. Anyone else have this happen?

  • Rich

    No a week and half wouldn’t make a difference.

  • Andrew Lee Lynch

    Do you use peptides? How long ? Any side effects you experienced ? Thinking of trying. Thanks

  • Rich

    Most this summer and haven’t had any negative side effects except certain kinds might increase appetite sometimes. I have mainly only positive effects like skin and body composition.

  • Pab

    Hi there seems to be a lot of sellers out there, would you recommend a brand or seller?

  • elementsarms

    Thanks for your valuable resources keep share the information like this…

  • Damien JordanTiger Duroux

    Definitely full of shit

  • Brandon

    I’ve been taking mod GRF 1-29 and ghrp-2 for 6 weeks, once daily at bedtime. I’m 44 years old, male, and in reasonably good condition, but by no means a gym rat. I have trimmed down a few pounds and definitely look leaner. My sleep is considerably better, much more restful, and I obtained a deep sleep that is rarely interrupted. I highly recommend trying these. I plan on staying on them for the rest of my life.

    Try xpeptides. I am in no way affiliated with the company, but they have an excellent reputation and reasonable prices. They test all of their products and will even show you the results of the testing.

  • darren colling

    Ive taken cjc 1295 have it made me tight chested, made red & rash.
    & queezy
    Anyone else had this

  • Danny

    Anyone used BPC157 and TB500? Are they safe eg safer than some of those mentioned here?

  • Nad Navlis

    All genuine peptides are safe. There may be a natural reaction to some. BPC and TB are VERY worthwhile when used for healing. From my results, I would use them even if they were somewhat unsafe. For those who suffered from what could have been lifelong debilitating injuries, they are a Godsend.

  • Nad Navlis

    Most likely a reaction to an impure peptide. It’s worthwhile paying a few dollars more for a manufacturer with a sterling reputation. There is a lot of bunk out there, so buyer beware.

  • Michelle Bates

    New to peptides and need advice on what to take. Do you just use one at a time or can your use 2 or 3 different ones? Also which is best??

  • Derek

    I have had immune system issues/ adrenal issues developed all types of sensitivites as well. So was lookin into peptides thogt about trying them to heal the adrenals then maybe to increase HGH as that heals alot of things ..Not sure if i should do adrenals, immune or Something for HGH (pituitary) ..Also where do you buy peptides

  • chelsea

    You can kill yourself more easily with most over the counter medicines then peptides in general.

  • chelsea

    This effect is had even with some pharma insulin injections… its an allergic reaction not a side effect of cjc

  • chelsea

    Add CJC without dac to your ghrp to get significantly better effects from it

  • chelsea

    If your fairly old an using ghrps you may experience extreme differences in hgh levels being on and off… but a week and a half? That radical body change is more like coming off a strong oral steroid with no pct in place.. you should probably get blood work done

  • chelsea

    appetite for me is a positive love ghrp-2 and 6 ghrelin spikes when trying to gain muscle

  • Dana Davis Kenney

    Yes!!! Today I had the worst reaction to Ipa/CJC1295- the Worst stomach pain for 1 hour with nausea… thought I would die!! Itching on my hands and feet and flushing…. it’s done this before. I just started back after 3 months, but literally can’t do it again!!!
    Going to go back to just Ipamorelin!!!
    Never had an issue with straight Ipa..
    Anyone else had SEVERE stomach pain with CJC??

  • Dana Davis Kenney

    Anyone had a bad reaction using CJC 1295?
    I did today…. ugh- BAD stomach pain from Hell and itching for an hour then it was gone…. not doing that again. Looking into something else for anti aging benefits and muscle tone/leanness.
    When I used just Ipa, had no reaction.
    Might try this Somadern Transdermal HGH Gel…

  • Lisa

    How do peptides decrease fertility? Can they make you infertile? I’m a woman using cjc1295 + ipamorelin and worried about this?

  • darcelle popoff

    Yes I gained weight and my
    appetite went thru the roof when I stopped I injecting ipamorelin

  • Jason Giannas

    Yes tight chested !! I woke up in the middle of the night and was like omg am i dying. Trying to relax. Anxious etc. Other than that its good but its a horrible feeling. I had to stop. Ive been on it 8 weeks
    Also my stomach gets gassy. It sucks so much because i was leaning out like crazy and lose weight.

  • Jeff

    How do you find a doctor that actually knows about peptides that can get you on the correct path???

  • Jennifer Lynn Carlson

    Anybody tried using PT-141 for libido??? I just ordered some! Excited at the possibilities but looking for irl reviews.

  • TheUsualSmearGame

    with DAC or no?

  • TheUsualSmearGame

    Do us a favor and list a few you trust. That would be helpful.

  • TheUsualSmearGame

    Most doctors want to throw pharma on you. Gotta get those free catered lunches somehow and trips to speak about their specialty in the Virgin Islands or Hawaii.


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